HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride → HCID 25026171, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride | HCID 21938415 | — |
| Reactant | HCID 59683592 | HCID 59683592 | — |
| Product | HCID 25026171 | HCID 25026171 | — |
Reaction Steps
Following the synthetic protocol described in Method D′; 3-Chloro-4,7-difluoro-benzo[b]thiophene-2-carboxylic acid [5-(2-fluoro-pyridin-3-yl)-2-methoxy-benzyl]-(4-methylamino-cyclohexyl)-amide is prepared starting from {4-[5-(2-Fluoro-pyridin-3-yl)-2-methoxy-benzylamino]-cyclohexyl}-methyl-carbamic acid tert-butyl ester and 3-Chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl chloride. The desired product is isolated in 45%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273747B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-940efade90754749989d1253128463d5 |
| Source note | uspto-grants-2012_09 |