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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2389678Generated: November 1, 2026

rac-tert-butyl N-methyl-N-[(1s,4s)-4-aminocyclohexyl]carbamate → HCID 59683625, compound

https://huagongshe.com/reaction/2389678

Reaction equation

Participants

RoleNameHCIDCharge
Reactantrac-tert-butyl N-methyl-N-[(1s,4s)-4-aminocyclohexyl]carbamateHCID 21938422—
Reactant5-(5-Fluoro-pyridin-3-yl)-2-methoxy-benzaldehydeHCID 54965923—
ProductHCID 59683625HCID 59683625—

Reaction Steps

Following the synthetic protocol described in Method C′; {4-[5-(5-Fluoro-pyridin-3-yl)-2-methoxy-benzylamino]-cyclohexyl}-methyl-carbamic acid tert-butyl ester is prepared starting from 5-(5-Fluoro-pyridin-3-yl)-2-methoxy-benzaldehyde and (4-Amino-cyclohexyl)-methyl-carbamic acid tert-butyl ester. The desired product is isolated in 64%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273747B2
Source datasetuspto-grants-2012_09
ORD IDord-93f5fe0f972f44178e7cac5d80254140
Source noteuspto-grants-2012_09