HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride → HCID 25025839, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride | HCID 21938415 | — |
| Reactant | HCID 59683487 | HCID 59683487 | — |
| Product | HCID 25025839 | HCID 25025839 | — |
Reaction Steps
Following the synthetic protocol described in Method D′; 3-Chloro-4,7-difluoro-benzo[b]thiophene-2-carboxylic acid [5-(3-fluoro-pyridin-4-yl)-2-methoxy-benzyl]-(4-methylamino-cyclohexyl)-amide is prepared starting from {4-[5-(3-Fluoro-pyridin-4-yl)-2-methoxy-benzylamino]-cyclohexyl}-methyl-carbamic acid tert-butyl ester and 3-Chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl chloride. The desired product is isolated in 54%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273747B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-eff3c94ff7eb4b3da87d4931768314d1 |
| Source note | uspto-grants-2012_09 |