(Pyridin-4-yl)boronic acid → HCID 59683593, compound

HRID 2389694Notes

Reaction equation

HRID 2389694 reaction equation
[N:1]1[CH:6]=[CH:5][C:4](B(O)O)=[CH:3][CH:2]=1.FC(F)(F)S(O[C:16]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[C:18]([CH:24]=[O:25])[CH:17]=1)(=O)=O>>[CH3:23][O:22][C:20]1[CH:19]=[C:18]([CH:17]=[C:16]([C:4]2[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=2)[CH:21]=1)[CH:24]=[O:25]

Participants

3

Reactant 2

HCID 2734379(Pyridin-4-yl)boronic acidHCID 59683490HCID 59683490, compound

Product 1

HCID 59683593HCID 59683593, compound

Procedure

Pyridine-4-boronic acid (50 mg, 0.35 mmol) is coupled to aryl triflate 241 (66 mg, 0.23 mmol) using Method A to give the title compound.

Sources & evidence

ORD record
ord-76a018f7f5964a2ba1f707c90d058f8c
Source dataset
uspto-grants-2012_09
Patent number
US08273747B2

Reaction notes

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