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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2389707Generated: October 31, 2026

5-Bromo-2-methylpyridine → tert-Butyl {4-[2-methoxy-5-(6-methyl-pyridin-3-yl)-benzylamino]-cyclohexyl}-methyl-carbamate

https://huagongshe.com/reaction/2389707

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-methylpyridineHCID 1201020—
Reactant3-{[4-(BOC-methyl-amino)-cyclohexylamino]-methyl}-4-methoxy-benzene boronic acidHCID 25208191—
Producttert-Butyl {4-[2-methoxy-5-(6-methyl-pyridin-3-yl)-benzylamino]-cyclohexyl}-methyl-carbamateHCID 59683457—

Reaction Steps

The title compound was prepared from boronic acid 4 (400 mg, 1.05 mmol) and 5-bromo-2-methylpyridine (181 mg, 1.05 mmol) in accordance with Method B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273747B2
Source datasetuspto-grants-2012_09
ORD IDord-eba0d5a5d8a34d15bdf77fcc7c7ac30b
Source noteuspto-grants-2012_09