HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromothioanisole → HCID 59766958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromothioanisole | HCID 88166 | — |
| Reactant | 3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride | HCID 21938415 | — |
| Reactant | 3-{[4-(BOC-methyl-amino)-cyclohexylamino]-methyl}-4-methoxy-benzene boronic acid | HCID 25208191 | — |
| Product | HCID 59766958 | HCID 59766958 | — |
Reaction Steps
Boronic acid 4 (300 mg, 0.76 mmol) was coupled to 2-bromothioanisole (156 mg, 0.77 mmol) using Method A. The crude reaction mixture was reacted with acid chloride 8 (246 mg, 0.92 mmol) using Method D to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273747B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-caaa479fd8c4462d85cebdd18145bb1c |
| Source note | uspto-grants-2012_09 |