3-(Trifluoromethoxy)benzene-1-sulfonyl chloride → N-[4-Methoxy-3-(1-propionyl-pyrrolidin-3-yl)-phenyl]-3-trifluoromethoxybenzenesulfonamide

Participants

Reaction Steps

1-[3-(2-Methoxy-5-amino-phenyl)-pyrrolidin-1-yl]-propan-1-one (0.44 g, 1.77 mmol) and commercially available 3-trifluoromethoxy-benzene sulfonylchloride (0.23 g, 0.89 mmol) were reacted as described above, to yield, after purification via silica gel chromatography using a ISCO Companion instrument, 0.198 g of the desired compound.

Provenance & Evidence