4-tert-Butylphenylboronic acid → HCID 59313103, compound

Participants

Reaction Steps

In analogy to the procedure described for Example 7, 34 mg (23% of theory) of the product are obtained starting from 120 mg (0.32 mmol) of N6-{2-[(7-chloro-2-methylimidazo[1,2-c]pyrimidin-5-yl)amino]ethyl}-3-nitropyridine-2,6-diamine (Example 31A) by coupling with 68 mg (0.38 mmol) of (4-tert-butylphenyl)boronic acid and subsequent purification by preparative HPLC.

Provenance & Evidence