HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)phenylboronic acid → HCID 59313121, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Reactant | HCID 59313149 | HCID 59313149 | — |
| Product | HCID 59313121 | HCID 59313121 | — |
Reaction Steps
In analogy to the preparation of Example 109, the desired product is prepared by Pd-catalysed coupling starting from ethyl 7-chloro-5-({2-[(5-cyanopyridin-2-yl)amino]ethyl}amino)-imidazo[1,2-c]pyrimidine-2-carboxylate (Example 59A) and [4-(trifluoromethyl)phenyl]boronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273752B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-947722eee4e945a38428a55b293ec123 |
| Source note | uspto-grants-2012_09 |