HCID 59179418, compound → HCID 59179438, compound

Participants

Reaction Steps

To a solution of (2E)-3-furo[3,2-c]pyridin-4-ylacrylamide (500 mg, 2.65 mmol) in acetic acid (5 mL) was added palladium-carbon powder (10 mg), and the mixture was stirred at room temperature for 14 hr under a hydrogen atmosphere. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (NH, methanol/ethyl acetate=3/97→15/85) to give the title compound (211 mg, yield 41%).

Provenance & Evidence