N-methoxy-N,3-dimethylbutanamide → 4-Methyl-1-(3-toluyl)-pentan-2-one

HRID 2390051Notes

Reaction equation

HRID 2390051 reaction equation
CON(C)[C:4](=[O:9])[CH2:5][CH:6]([CH3:8])[CH3:7].[CH3:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[CH2:15][Mg]Cl>>[CH3:7][CH:6]([CH3:8])[CH2:5][C:4](=[O:9])[CH2:11][C:12]1[CH:13]=[C:14]([CH3:15])[CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 10975620N-methoxy-N,3-dimethylbutanamideHCID 178425037HCID 178425037, compound

Product 1

HCID 392382934-Methyl-1-(3-toluyl)-pentan-2-one

Procedure

The reaction and treatment were carried out in the same manner as in Example 36-b) using N-methoxy-N-methyl-3-methylbutanamide and 3-methylbenzyl magnesium chloride to obtain a title compound as a light yellow oily substance.

Workup

  1. customThe reaction and treatment

Sources & evidence

ORD record
ord-41b937c61668408b8e609de182fa49cf
Source dataset
uspto-grants-2012_09
Patent number
US08273766B2

Reaction notes

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