Phenyl isocyanate → HCID 59323206, compound

Participants

Reaction Steps

To a solution of 30 mg of 2-[3-benzyl-3,4-dihydroisoquinolin-2(1H)-yl]ethanamine obtained in Example 1-f) in 1 mL of methylene chloride was added 13.8 mg of phenyl isocyanate at room temperature, followed by stirring at room temperature for 1 hour. After completion of the reaction, the reaction liquid was concentrated under reduced pressure. The residue obtained was purified using PLC (chloroform:methanol=10:1) to obtain 32.2 mg (yield 60%) of a title compound as a pale yellow oily substance.

Provenance & Evidence