Phenethyl isocyanate → HCID 59323241, compound

HRID 2390076Notes

Reaction equation

HRID 2390076 reaction equation
[F:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][CH:7]2[CH2:16][C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[CH2:9][N:8]2[CH2:17][CH2:18][NH2:19])=[CH:4][CH:3]=1.[CH2:22]([N:30]=[C:31]=[O:32])[CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[F:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][CH:7]2[CH2:16][C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[CH2:9][N:8]2[CH2:17][CH2:18][NH:19][C:31]([NH:30][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:32])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 160602Phenethyl isocyanateHCID 59323164HCID 59323164, compound

Product 1

HCID 59323241HCID 59323241, compound

Procedure

The reaction and treatment were carried out in the same manner as in Example 208 using 2-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]ethanamine obtained in Example 210-a) as a starting material, and using phenethyl isocyanate instead of phenyl isocyanate to obtain a title compound as a pale yellow amorphous substance.

Workup

  1. customThe reaction and treatment

Sources & evidence

ORD record
ord-4cd1aa12532b49d586d30eef183505c4
Source dataset
uspto-grants-2012_09
Patent number
US08273766B2

Reaction notes

Loading…