HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethyl isocyanate → 1-[3-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propyl]-3-(2-phenyl ethyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethyl isocyanate | HCID 160602 | — |
| Reactant | 3-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propanamine | HCID 59323365 | — |
| Product | 1-[3-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propyl]-3-(2-phenyl ethyl)urea | HCID 59323417 | — |
Reaction Steps
The reaction and treatment were carried out in the same manner as in Example 208 using 3-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propanamine obtained in Example 214-b) as a starting material, and using phenethyl isocyanate instead of phenyl isocyanate to obtain a title compound as a pale yellow amorphous substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273766B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-9702e3b53f574fcab389bb265c56729c |
| Source note | uspto-grants-2012_09 |