HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethylphenyl isocyanate → 1-(2-ethyl phenyl)-3-[3-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propyl]urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethylphenyl isocyanate | HCID 583486 | — |
| Reactant | 3-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propanamine | HCID 59323365 | — |
| Product | 1-(2-ethyl phenyl)-3-[3-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propyl]urea | HCID 59323469 | — |
Reaction Steps
The reaction and treatment were carried out in the same manner as in Example 208 using 3-[3-(4-fluorobenzyl)-3,4-dihydroisoquinolin-2(1H)-yl]propanamine obtained in Example 214-b) as a starting material, and using 2-ethylphenyl isocyanate instead of phenyl isocyanate to obtain a title compound as a pale yellow amorphous substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273766B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-30de7d96824b4606862abaac3e476962 |
| Source note | uspto-grants-2012_09 |