Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Bromo-4-(hex-1-en-1-yl)pyridine → 3-Bromo-4-hexylpyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Bromo-4-(hex-1-en-1-yl)pyridine | HCID 67008079 | — |
| 촉매 | Adams' catalyst | HCID 345198 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 3-Bromo-4-hexylpyridine | HCID 58521884 | — |
반응 단계
A mixture of 3-bromo-4-(hex-1-en-1-yl)pyridine (Intermediate 12; 360 mg; 1.50 mmol) and platinum dioxide (34 mg; 0.15 mmol) in EtOAc (35 mL) was hydrogenated at 7 atm for 1 hour in a PARR apparatus. The reaction mixture was filtered, evaporated and purified by flash column chromatography, eluting with cyclohexane containing increasing amounts of EtOAc, affording the title compound as a colorless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08273769B2 |
| 출처 데이터셋 | uspto-grants-2012_09 |
| ORD ID | ord-62c1d9b9b9674a1fa1e1a583be010cc2 |
| 출처 메모 | uspto-grants-2012_09 |