HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl{4-chloro-2-[(trimethylsilyl)ethynyl]phenoxy}acetate → 2-Trimethylsilylethynyl-1-methyl-4-(propylsulfonyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl{4-chloro-2-[(trimethylsilyl)ethynyl]phenoxy}acetate | HCID 56594380 | — |
| Reactant | 2-Bromo-1-methyl-4-(propylsulfonyl)benzene | HCID 58522091 | — |
| Product | 2-Trimethylsilylethynyl-1-methyl-4-(propylsulfonyl)benzene | HCID 58522037 | 75% |
Reaction Steps
Following the general method as outlined in Intermediate 2, starting from 2-bromo-1-methyl-4-(propylsulfonyl)benzene (Intermediate 37) and trimethylsilylacetilene, the title compound was obtained as a brown liquid in 75% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-1514f0eb6b344b8c8b809265320dca2b |
| Source note | uspto-grants-2012_09 |