HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylsilylacetylene → Tert-butyl{4-cyano-2-[(trimethylsilyl)ethynyl]phenoxy}acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylsilylacetylene | HCID 66111 | — |
| Reactant | Tert-butyl{4-chloro-2-[(trimethylsilyl)ethynyl]phenoxy}acetate | HCID 56594380 | — |
| Reactant | Tert-butyl 2-(2-bromo-4-cyanophenoxy)acetate | HCID 58521856 | — |
| Product | Tert-butyl{4-cyano-2-[(trimethylsilyl)ethynyl]phenoxy}acetate | HCID 58521908 | 87% |
Reaction Steps
Following the general method as outlined in Intermediate 2, starting from tert-butyl(2-bromo-4-cyanophenoxy)acetate (Intermediate 44) and (trimethylsilyl)acetylene (Aldrich), the title compound was obtained as a dark brown sticky solid in 87% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-47256b9790624be4800c2434eaef6e3f |
| Source note | uspto-grants-2012_09 |