Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2390168Generated: October 29, 2026

Tert-butyl(4-chloro-2-ethynylphenoxy)acetate → HCID 58521958, compound

https://huagongshe.com/reaction/2390168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl(4-chloro-2-ethynylphenoxy)acetateHCID 56594381—
ReactantHCID 59216691HCID 59216691—
ProductHCID 58521958HCID 58521958—

Reaction Steps

Following the general method as outlined in Intermediate 79, starting from (4-chloro-2-ethynyl-phenoxy)-acetic acid tert-butyl ester (Intermediate 3) and 2-iodo-4-(methylsulfonyl)phenol (Intermediate 78), the title compound was obtained after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273769B2
Source datasetuspto-grants-2012_09
ORD IDord-d973625929354b6b9e273800820e56e7
Source noteuspto-grants-2012_09