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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2390176Generated: October 29, 2026

2-Isopropenyl-5-(methylsulfonyl)aniline → 2-Isopropyl-5-(methylsulfonyl)aniline

https://huagongshe.com/reaction/2390176

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Isopropenyl-5-(methylsulfonyl)anilineHCID 58521961—
Reactant5-(Methylsulfonyl)-2-propylanilineHCID 58522006—
Product2-Isopropyl-5-(methylsulfonyl)anilineHCID 2835591181%

Reaction Steps

Following the general method as outlined in Intermediate 61, starting from 2-isopropenyl-5-(methylsulfonyl)aniline (Intermediate 89), the title compound was obtained as a green solid in 81% yield after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273769B2
Source datasetuspto-grants-2012_09
ORD IDord-e86db1a49f5f49c3a923685c1533ac4a
Source noteuspto-grants-2012_09