HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-tert-Butylphenyl glycidyl ether → Phenyl glycidyl ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-tert-Butylphenyl glycidyl ether | HCID 18360 | — |
| Reactant | 3-Methyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide | HCID 67378205 | — |
| Product | Phenyl glycidyl ether | HCID 31217 | — |
| Product | 3-isopropyl-2-oxo-N-(piperidin-4-ylmethyl)-2,3-dihydro-1H-benzimidazole-1-carboxamide | HCID 44249188 | — |
Reaction Steps
The procedure given in Example 104 was followed using 3-methyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 4-tert-butylphenyl glycidyl ether as a reactant, instead of 3-isopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 1,2-epoxy-3-phenoxypropane, to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642772B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-6462c081828f4f7ba6865ac5dffb3d6a |
| Source note | uspto-grants-2014_02 |