HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-N,N,4-trimethylbenzene-1-sulfonamide → HCID 58522002, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-N,N,4-trimethylbenzene-1-sulfonamide | HCID 7213305 | — |
| Reactant | Tert-butyl(4-chloro-2-ethynylphenoxy)acetate | HCID 56594381 | — |
| Product | HCID 58522002 | HCID 58522002 | — |
Reaction Steps
Following the general method as outlined in Intermediate 20, starting from (4-chloro-2-ethynyl-phenoxy)-acetic acid tert-butyl ester (Intermediate 3) and N,N-dimethyl 3-bromo-4-methylbenzenesulfonamide (Combiblocks), the title compound was obtained as an orange sticky solid after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-f8db246070a042ab94d41cb2b771f3b0 |
| Source note | uspto-grants-2012_09 |