HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-ISOPROPYL 3-BROMO-4-METHYLBENZENESULFONAMIDE → HCID 58521991, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-ISOPROPYL 3-BROMO-4-METHYLBENZENESULFONAMIDE | HCID 7213291 | — |
| Reactant | Tert-butyl(4-chloro-2-ethynylphenoxy)acetate | HCID 56594381 | — |
| Product | HCID 58521991 | HCID 58521991 | — |
Reaction Steps
Following the general method as outlined in Intermediate 20, starting from (4-chloro-2-ethynyl-phenoxy)-acetic acid tert-butyl ester (Intermediate 3) and N-isopropyl 3-bromo-4-methylbenzenesulfonamide (Combiblocks), the title compound was obtained as an orange sticky solid after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-541e86245bf7406e96122bf1b9cfee90 |
| Source note | uspto-grants-2012_09 |