HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Chlorothiophenol → Benzene, 1-chloro-4-(propylsulfonyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Chlorothiophenol | HCID 7815 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | 1-Fluoro-4-(propylsulfonyl)benzene | HCID 14289525 | — |
| Product | Benzene, 1-chloro-4-(propylsulfonyl)- | HCID 21041456 | 82% |
Reaction Steps
Following the general method as outlined in Intermediate 105, starting from 4-chlorothiophenol (Aldrich) and 1-iodopropane, the title compound was obtained as an oil which solidified upon standing in 82% yield after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-84eb0190c2e14753b9e212dfd65a6b48 |
| Source note | uspto-grants-2012_09 |