Benzene, 1-chloro-4-(propylsulfonyl)- → 2-Bromo-1-chloro-4-(propylsulfonyl)benzene

HRID 2390207Notes

Reaction equation

HRID 2390207 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([S:8]([CH2:11][CH2:12][CH3:13])(=[O:10])=[O:9])[CH:5]=[CH:4][C:3]=1F.[Cl:15]C1C=CC(S(CCC)(=O)=O)=CC=1>>[Br:1][C:2]1[CH:7]=[C:6]([S:8]([CH2:11][CH2:12][CH3:13])(=[O:10])=[O:9])[CH:5]=[CH:4][C:3]=1[Cl:15]

Participants

3

Reactant 2

HCID 21041456Benzene, 1-chloro-4-(propylsulfonyl)-2×HCID 585220712-Bromo-1-fluoro-4-(propylsulfonyl)benzene

Product 1

HCID 585220882-Bromo-1-chloro-4-(propylsulfonyl)benzeneYield 86%

Procedure

Following the general method as outlined in Intermediate 106, starting from 1-chloro-4-(propylsulfonyl)benzene (Intermediate 125), the title compound was obtained as an oil which solidified upon standing in 86% yield.

Sources & evidence

ORD record
ord-0d4bbb0cbcce4c0880f6f4a27f376e3b
Source dataset
uspto-grants-2012_09
Patent number
US08273769B2

Reaction notes

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