HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-bromo-N,N-dimethylbenzamide → HCID 58521862, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-bromo-N,N-dimethylbenzamide | HCID 140389 | — |
| Reactant | Tert-butyl(4-chloro-2-ethynylphenoxy)acetate | HCID 56594381 | — |
| Product | HCID 58521862 | HCID 58521862 | — |
Reaction Steps
Following the general method as outlined in Intermediate 20, starting from (4-chloro-2-ethynyl-phenoxy)-acetic acid tert-butyl ester (Intermediate 3) and 4-bromo-N,N-dimethylbenzamide (Intermediate 176), the title compound was obtained as a brown sticky solid after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-60d5434e9b8347c9a1f6b652f86b323d |
| Source note | uspto-grants-2012_09 |