Dimethylamine → 3-bromo-N,N-dimethylbenzamide

HRID 2390238노트

반응식

Br[C:2]1[CH:15]=[CH:14][C:5]([C:6]([N:8]2[CH2:13]COC[CH2:9]2)=[O:7])=[CH:4][CH:3]=1.[Br:16]C1C=C(C=CC=1)C(Cl)=O.CNC>>[Br:16][C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:2]=1)[C:6]([N:8]([CH3:13])[CH3:9])=[O:7]

참가 물질

반응물 3

HCID 674Dimethylamine

HCID 74377Benzoyl chloride, 3-bromo-

HCID 5321484-(4-Bromobenzoyl)morpholine

생성물 1

HCID 33358263-bromo-N,N-dimethylbenzamide수율 85%

실험 절차

Following the general method as outlined in Intermediate 174, starting from 3-bromobenzoyl chloride and dimethylamine, the title compound was obtained as a orange sticky solid in 85% yield.

출처 및 근거

ORD 기록: ord-45cbbc15817f4d2185f7d882de003a09
출처 데이터셋: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08273769B2

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