HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-bromo-N,N-dimethylbenzamide → HCID 58521976, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-bromo-N,N-dimethylbenzamide | HCID 3335826 | — |
| Reactant | Tert-butyl(4-chloro-2-ethynylphenoxy)acetate | HCID 56594381 | — |
| Product | HCID 58521976 | HCID 58521976 | — |
Reaction Steps
Following the general method as outlined in Intermediate 20, starting from (4-chloro-2-ethynyl-phenoxy)-acetic acid tert-butyl ester (Intermediate 3) and 3-bromo-N,N-dimethylbenzamide (Intermediate 180), the title compound was obtained as a brown sticky solid after purification by flash column chromatography (silica), eluting with cyclohexane containing increasing amounts of EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-7e477b5d4ae94c7f8f66875eaa2441cd |
| Source note | uspto-grants-2012_09 |