1-chloro-2-nitro-4-[(trifluoromethyl)sulfonyl]benzene → 2-Chloro-5-(trifluoromethylsulfonyl)aniline

HRID 2390243Notes

Reaction equation

HRID 2390243 reaction equation
FC1C=CC(S(C)(=O)=O)=CC=1N.[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([C:23]([F:26])([F:25])[F:24])(=[O:22])=[O:21])=[CH:16][C:15]=1[N+:27]([O-])=O>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([C:23]([F:25])([F:24])[F:26])(=[O:22])=[O:21])=[CH:16][C:15]=1[NH2:27]

Participants

3

Reactant 2

HCID 15479561-chloro-2-nitro-4-[(trifluoromethyl)sulfonyl]benzeneHCID 27746372-Fluoro-5-(methylsulfonyl)aniline

Product 1

HCID 20632962-Chloro-5-(trifluoromethylsulfonyl)aniline

Procedure

Following the general method as outlined in Intermediate 76, starting from 1-chloro-2-nitro-4-[(trifluoromethyl)sulfonyl]benzene (MDA), the title compound was obtained as a brown solid in quantitative yield.

Sources & evidence

ORD record
ord-426860906e1145fcb96c596abcf09e42
Source dataset
uspto-grants-2012_09
Patent number
US08273769B2

Reaction notes

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