HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4'-Dichloropropiophenone → 3-Chloropropiophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4'-Dichloropropiophenone | HCID 77550 | — |
| Reactant | 3-isopropyl-2-oxo-N-(piperidin-4-ylmethyl)-2,3-dihydro-1H-benzimidazole-1-carboxamide | HCID 44249188 | — |
| Product | 3-Chloropropiophenone | HCID 70295 | — |
| Product | 3-Cyclopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide | HCID 67369254 | — |
Reaction Steps
The procedure given in Example 135 was followed using 3-isopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 3-chloro-4′-chloropropiophenone as a reactant, instead of 3-cyclopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 3-chloropropiophenone, to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642772B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-bc46462275ee4941b83713dfb0bdd50e |
| Source note | uspto-grants-2014_02 |