Morpholine → HCID 58521835, compound

HRID 2390310Notes

Reaction equation

HRID 2390310 reaction equation
[Br:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([N:8]([CH2:10][CH2:11]CC)[CH3:9])=[O:7])=[C:4]([S:16]([CH:19]([CH3:21])[CH3:20])(=[O:18])=[O:17])[CH:3]=1.BrC1C=CC([C:27](O)=[O:28])=C(S(C(C)C)(=O)=O)C=1.N1CCOCC1>>[Br:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([N:8]2[CH2:9][CH2:27][O:28][CH2:11][CH2:10]2)=[O:7])=[C:4]([S:16]([CH:19]([CH3:21])[CH3:20])(=[O:18])=[O:17])[CH:3]=1

Participants

4

Reactant 3

HCID 8083MorpholineHCID 56594115HCID 56594115, compound2×HCID 58521909HCID 58521909, compound

Product 1

HCID 58521835HCID 58521835, compound

Procedure

Following the general method as outlined in Intermediate 253, starting from 4-bromo-2-(isopropylsulfonyl)benzoic acid (Intermediate 242) and morpholine, the title compound was obtained as a pink solid.

Sources & evidence

ORD record
ord-0e3a70f801944a59bb5b999755e2a0bf
Source dataset
uspto-grants-2012_09
Patent number
US08273769B2

Reaction notes

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