HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl(4-cyano-2-ethynylphenoxy)acetate → (4-Cyano-2-{[2-methyl-5-(propylsulfonyl)phenyl]ethynyl}phenoxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl(4-cyano-2-ethynylphenoxy)acetate | HCID 58522073 | — |
| Reactant | 2-Bromo-1-methyl-4-(propylsulfonyl)benzene | HCID 58522091 | — |
| Product | (4-Cyano-2-{[2-methyl-5-(propylsulfonyl)phenyl]ethynyl}phenoxy)acetic acid | HCID 56595443 | — |
Reaction Steps
Following the general method as outlined in Example 37, starting from 2-bromo-1-methyl-4-(propylsulfonyl)benzene (Intermediate 37) and tert-butyl(4-cyano-2-ethynylphenoxy)acetate (Intermediate 46), the title compound was obtained as a white solid after purification by preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-9ad030ddda4f48f685810f409309b2cd |
| Source note | uspto-grants-2012_09 |