HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl(4-chloro-2-ethynylphenoxy)acetate → (4-Chloro-2-{[5-(isopropylsulfonyl)-2-methylphenyl]ethynyl}phenoxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl(4-chloro-2-ethynylphenoxy)acetate | HCID 56594381 | — |
| Reactant | 2-Bromo-4-(isopropylsulfonyl)-1-methylbenzene | HCID 58522059 | — |
| Product | (4-Chloro-2-{[5-(isopropylsulfonyl)-2-methylphenyl]ethynyl}phenoxy)acetic acid | HCID 46865973 | — |
Reaction Steps
Following the general method as outlined in Example 37, starting from tert-butyl(4-chloro-2-ethynyl phenoxy)acetate (Intermediate 3) and 2-bromo-4-(isopropylsulfonyl)-1-methylbenzene (Intermediate 64), the title compound was obtained as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273769B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-1d5a963bff6e46bc96efb0b421008a10 |
| Source note | uspto-grants-2012_09 |