Tert-butyl(4-chloro-2-ethynylphenoxy)acetate → HCID 56594780, compound

HRID 2390345Notes

Reaction equation

HRID 2390345 reaction equation
C([O:5][C:6](=[O:18])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=1[C:16]#[CH:17])(C)(C)C.Br[C:20]1[CH:21]=[C:22]([S:27]([CH2:30][CH2:31][OH:32])(=[O:29])=[O:28])[CH:23]=[CH:24][C:25]=1[CH3:26]>>[Cl:15][C:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][C:6]([OH:5])=[O:18])=[C:10]([C:16]#[C:17][C:20]2[CH:21]=[C:22]([S:27]([CH2:30][CH2:31][OH:32])(=[O:29])=[O:28])[CH:23]=[CH:24][C:25]=2[CH3:26])[CH:11]=1

Participants

3

Reactant 2

HCID 56594381Tert-butyl(4-chloro-2-ethynylphenoxy)acetate2×HCID 58522064HCID 58522064, compound2×

Product 1

HCID 56594780HCID 56594780, compound

Procedure

Following the general method as outlined in Example 37, starting from tert-butyl(4-chloro-2-ethynyl phenoxy)acetate (Intermediate 3) and 2-[(3-bromo-4-methylphenyl)sulfonyl]ethanol (Intermediate 67), the title compound was obtained as a yellow solid.

Sources & evidence

ORD record
ord-ac85586db898497d9f24ff03d62128aa
Source dataset
uspto-grants-2012_09
Patent number
US08273769B2

Reaction notes

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