Tert-butyl(4-chloro-2-ethynylphenoxy)acetate → HCID 56594653, compound

HRID 2390361Notes

Reaction equation

HRID 2390361 reaction equation
C([O:5][C:6](=[O:18])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=1[C:16]#[CH:17])(C)(C)C.[CH2:19]([S:26]([C:29]1[CH:34]=[CH:33][C:32]([CH3:35])=[C:31](Br)[CH:30]=1)(=[O:28])=[O:27])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:19]([S:26]([C:29]1[CH:34]=[CH:33][C:32]([CH3:35])=[C:31]([C:17]#[C:16][C:10]2[CH:11]=[C:12]([Cl:15])[CH:13]=[CH:14][C:9]=2[O:8][CH2:7][C:6]([OH:5])=[O:18])[CH:30]=1)(=[O:28])=[O:27])[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 56594381Tert-butyl(4-chloro-2-ethynylphenoxy)acetate2×HCID 58521922HCID 58521922, compound2×

Product 1

HCID 56594653HCID 56594653, compound

Procedure

Following the general method as outlined in Example 37, starting from tert-butyl(4-chloro-2-ethynyl phenoxy)acetate (Intermediate 3) and 4-(benzylsulfonyl)-2-bromo-1-methylbenzene (Intermediate 69), the title compound was obtained as a yellow solid.

Sources & evidence

ORD record
ord-2b83e1c544de40a686469d811fefacc2
Source dataset
uspto-grants-2012_09
Patent number
US08273769B2

Reaction notes

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