HCID 58521922, compound → HCID 58521834, compound

HRID 2390363Notes

Reaction equation

HRID 2390363 reaction equation
C([O:5][C:6](=[O:19])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]#[N:16])=[CH:11][C:10]=1[C:17]#[CH:18])(C)(C)C.[CH2:20]([S:27]([C:30]1[CH:35]=[CH:34][C:33]([CH3:36])=[C:32](Br)[CH:31]=1)(=[O:29])=[O:28])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:20]([S:27]([C:30]1[CH:35]=[CH:34][C:33]([CH3:36])=[C:32]([C:18]#[C:17][C:10]2[CH:11]=[C:12]([C:15]#[N:16])[CH:13]=[CH:14][C:9]=2[O:8][CH2:7][C:6]([OH:5])=[O:19])[CH:31]=1)(=[O:29])=[O:28])[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 58521922HCID 58521922, compound2×HCID 58522073Tert-butyl(4-cyano-2-ethynylphenoxy)acetate2×

Product 1

HCID 58521834HCID 58521834, compound

Procedure

Following the general method as outlined in Example 37, starting from tert-butyl(4-cyano-2-ethynyl phenoxy)acetate (Intermediate 46) and 4-(benzylsulfonyl)-2-bromo-1-methylbenzene (Intermediate 69), the title compound was obtained as a yellow solid.

Sources & evidence

ORD record
ord-8d3c1f8c9d9f4fc8b979e62a2a87efb0
Source dataset
uspto-grants-2012_09
Patent number
US08273769B2

Reaction notes

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