3-(3-Tert-butyl-4-methoxy-5-nitrophenyl)-2-methoxypyridine → 3-Tert-butyl-2-methoxy-5-(2-methoxypyridin-3-yl)phenylamine

Participants

Reaction Steps

step 2—To a solution of 98 (0.98 g, 3.1 mmol) in EtOAc/MeOH (2:1, 30 mL) was added 10% Pd/C (0.10 g). A stream of hydrogen gas was bubbled through the solution for 20 min then the solution was stirred at RT for 16 h. The reaction mixture was filtered and concentrated to afford 3-tert-butyl-2-methoxy-5-(2-methoxypyridin-3-yl)phenylamine (100).

Provenance & Evidence