HCID 67287575, compound → HCID 68574130, compound

Participants

Reaction Steps

step a—A solution of 199 (0.042 g) in 1 N LiOH (1 mL), MeOH (1 mL) and THF (1 mL) was stirred at 50° C. for 3 h, cooled and concentrated in vacuo. The solution was acidified and extracted with EtOAc. The extracts were washed with brine, dried, filtered and evaporated to afford 2-{(E-2-[3-(2-benzyloxy-pyridin-3-yl)-5-tert-butyl-phenyl]-vinyl}-5-methanesulfonylamino-benzoic acid (199a).

Provenance & Evidence