HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Oxo-1,2-dihydropyridin-3-yl)boronic acid → HCID 67069968, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Oxo-1,2-dihydropyridin-3-yl)boronic acid | HCID 55262735 | — |
| Reactant | HCID 67287059 | HCID 67287059 | — |
| Product | HCID 67069968 | HCID 67069968 | — |
Reaction Steps
step 3—Palladium-catalyzed coupling of 212 and B-(1,2-dihydro-2-oxo-3-pyridinyl)-boronic acid (213, CASRN 951655-49-5) was carried out in accord with the procedure in step 4 of example 38 to afford the title compound. The product was purified on a SiO2 preparative TLC plate developed with 5% MeOH/DCM to afford 17.5 mg of I-160
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273773B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-399be2dcb6e94c8394bb86e794633d7e |
| Source note | uspto-grants-2012_09 |