HCID 67070321, compound → HCID 67069921, compound

Participants

Reaction Steps

step 4—To a solution of 320 (86 mg, 0.148 mmol) in a mixture of MeOH/EtOAc (2 mL and 1 mL, respectively) at RT was added 20% palladium (II) hydroxide on carbon (moist) (9 mg, 10 wt. %). The reaction mixture was stirred under 1 atm of H2 for 1.5 h. The reaction mixture was filtered through a plug of CELITE and the pad washed with EtOAc. The filtrate was concentrated to afford 72 mg (99%) of I-251 as a light pink solid.

Provenance & Evidence