1,4-Dioxane hydrochloride → HCID 67070371, compound

Participants

Reaction Steps

step 3—To a solution of 342 (0.886 g, 1.266 mmol and DCM (10 mL) at RT was added a HCl/dioxane solution (1.899 mL, 7.60 mmol, 4M solution) and the resulting solution stirred at RT for 3 h. The resulting solution was poured into DCM (150 mL) which produced a gummy oil. When the mixture was sonicated a white powder formed which was filtered, washed with DCM and air-dried. The solid was dried under high vacuum to remove all traces of solvent which afforded 698 g of II-7 as a white powder: MS (M+H)=600.

Provenance & Evidence