Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-(2-Azatricyclo[3.3.1.13,7]dec-2-yl)-2,2,2-trichloroethanone | HCID 68637859 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 637989 | HCID 637989 | 77% |
Reaction Steps
A solution containing 23.4 g (83 mmol) of N-trichloroacetyl-2-azaadamantane and 70.1 g of isopropanol, was heated to 80° C., and 99.4 g of a 20 wt % NaOH aqueous solution was added, followed by stirring for one hour. 47 g of water and 47 g of toluene were added, followed by liquid separation, to obtain a toluene solution of 2-azaadamantane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08273889B2 |
|---|
| Source dataset | uspto-grants-2012_09 |
|---|
| ORD ID | ord-13d1a688cba444e894d3671cb837445c |
|---|
| Source note | uspto-grants-2012_09 |
|---|
