HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 2-Chloronicotinoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-Chloronicotinic acid | HCID 76258 | — |
| Product | 2-Chloronicotinoyl chloride | HCID 2774541 | 98% |
Reaction Steps
2-Chloronicotinic acid (317 mmol) was diluted with oxalyl chloride (130 mL) and the resulting solution was heated at reflux for 18 h. The volatiles were removed by evaporation to provide 2-chloronicotinoyl chloride in 98% yield as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273891B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-53ac13aba75640c28b9961d85b68a664 |
| Source note | uspto-grants-2012_09 |