HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → 4,5,6,7-Tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-amine dihydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 3-Bromopiperidin-4-one hydrobromide | HCID 14196968 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4,5,6,7-Tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-amine dihydrobromide | HCID 46736051 | 84.9% |
Reaction Steps
4.55 g thiourea was added to 15.2 g 3-Bromo-piperidin-4-one hydrobromide in 152 mL ethanol and refluxed for 20 h. The reaction was cooled and the solid was filtered, washed with ethanol and dried to give 15.8 g of the desired product., (M+H)+: 184
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642774B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-82ccc37c36934afb9a5db2670d12ed21 |
| Source note | uspto-grants-2014_02 |