HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → Benzyl 3-(methylamino)but-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Benzyl acetoacetate | HCID 142266 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Benzyl 3-(methylamino)but-2-enoate | HCID 66660284 | 96.8% |
Reaction Steps
To benzyl acetoacetate (29 g, 151 mmol) in ethanol (30 mL) was added methyl amine (33% in ethanol, 7.02 g, 226 mmol). The solution was stirred for 2 hours at room temperature followed by evaporation to yield a yellow oil (˜30 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273780B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-fcbee985fa67416690699ca4a74f9300 |
| Source note | uspto-grants-2012_09 |