HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetylbenzonitrile → 3-(1-hydroxyethyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetylbenzonitrile | HCID 80222 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(1-hydroxyethyl)benzonitrile | HCID 11228875 | — |
Reaction Steps
To a solution of 3-acetylbenzonitrile (1 equivalent) in methanol at room temperature was added sodium borohydride (approx. 1.67 equivalents), and the reaction was stirred for approximately 20 minutes. Aqueous work-up provided the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273780B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-735204e5cd3c49009689f1c4d3eca6b6 |
| Source note | uspto-grants-2012_09 |