4-Bromobenzoyl chloride → HCID 66577727, compound

HRID 2391092Notes

Reaction equation

HRID 2391092 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[O:11]=[C:12]([CH2:18][CH3:19])[CH2:13][C:14]([O:16][CH3:17])=[O:15].CC(C)([O-])C.[Na+]>>[CH3:17][O:16][C:14](=[O:15])[CH:13]([C:6](=[O:7])[C:5]1[CH:9]=[CH:10][C:2]([Br:1])=[CH:3][CH:4]=1)[C:12](=[O:11])[CH2:18][CH3:19]

Participants

4

Reactant 3

HCID 685154-Bromobenzoyl chlorideHCID 121699Methyl 3-oxovalerateHCID 23676156Sodium t-butoxide

Product 1

HCID 66577727HCID 66577727, compound

Procedure

Prepared according to the procedure described in Example 1, Step 2 using 4-bromobenzoyl chloride and methyl 3-oxovalerate; sodium tert-butoxide was used in place of pyridine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-acbb1e20f21f462984779205c3701574
Source dataset
uspto-grants-2012_09
Patent number
US08273780B2

Reaction notes

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