反应详情

2 g palladium charcoal was added to 7.3 g 3-(1-benzyl-piperidin-4-yl)-1-methyl-3,4-dihydro-1H-quinazolin-2-one in 150 mL methanol and stirred for 5 h under 50 psi hydrogen atmosphere. The mixture was filtered and the solvent was removed. Diethylether was added and the precipate was filtered to yield 3.4 g of the desired product.

1. filtrationThe mixture was filtered
2. customthe solvent was removed
3. additionDiethylether was added
4. filtrationthe precipate was filtered