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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391153Generated: October 31, 2026

Methanol → HCID 57441041, compound

https://huagongshe.com/reaction/2391153

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 57441040HCID 57441040—
SolventWaterHCID 962—
ProductHCID 57441041HCID 5744104190.5%

Reaction Steps

Using methyl 3-(1-cyanocyclohexyl)benzoate (1.3 g, 5.3 mmol), lithium hydroxide-monohydrate (0.52 g, 13 mmol), tetrahydrofuran (18 mL), methanol (6.0 mL) and water (6.0 mL) as starting materials and in the same manner as in Reference Example 37, the title compound (1.1 g, 88%) was obtained as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273741B2
Source datasetuspto-grants-2012_09
ORD IDord-241e7baba6864ae9a1db7558a202c649
Source noteuspto-grants-2012_09