HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → N-[6-(3-aminophenoxy)imidazo[1,2-b]pyridazin-2-yl]-2-methoxyacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)-2-methoxyacetamide | HCID 57441027 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-[6-(3-aminophenoxy)imidazo[1,2-b]pyridazin-2-yl]-2-methoxyacetamide | HCID 57505512 | 51.1% |
Reaction Steps
Using N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)-2-methoxyacetamide (0.60 g, 1.81 mmol), N,N-dimethylformamide (6.0 mL), potassium carbonate (499 mg, 3.61 mmol) and 3-aminophenol (296 mg, 2.71 mmol) as starting materials and in the same manner as in Example 91, the title compound (0.29 g, 51%) was obtained as a dark brown powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273741B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-86f6e382fcb44e3d8673b93461f80e34 |
| Source note | uspto-grants-2012_09 |